Pyrrolopyrimidine Nucleosides 19.1 a Total Synthesis of the Nucleoside Antibiotic Cadeguomycin [z-amino-7-(b-d-ribofuranosyl)- Pyrrolo[2,3-~]pyrimidin-4-one-5-carboxylic Acid]
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چکیده
Vladimir G. Beylin, Andrew M. Kawasaki, Chin Shu Cheng, and Leroy B. Townsend* Department of Medicinal Chemistry, College of Pharmacy, and Department of Chemistry University of Michigan, Ann Arbor, Michigan 48109 Abstract. A total synthesis of 2-amino-7-(O-D-ribofuranosyl)pyrrolo[2,3-dlpyrimidin-4-one5-carboxylic acid has been accomplished and confirms the previous structural assignment for the nucleoside antibiotic cadeguomycin.
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